Erythromycin tablets 100 mg #10

Erythromycin tablets 100 mg #10
Manufactured by: Russia / Ukraine
Product Code: 11784
$1.04

Qty:  BUY
You can buy Erythromycin tablets 100 mg #10 here.

 

Pharmacological action
 
Macrolide antibiotics. Bacteriostatic action. However, at higher doses against susceptible organisms has a bactericidal effect. Erythromycin is reversibly bound to the ribosome of bacteria, thereby inhibiting protein synthesis. The spectrum of activity includes Gram-positive (Staphylococcus spp., Producing and not producing penicillinase; Streptococcus spp., Including S.pneumoniae, Clostridium spp., Bacillus anthracis, Corynebacterium diphtheriae) and some Gram-negative bacteria (Neisseria gonorrhoeae, Haemophilus influenzae, Bordetella pertussis, Brucella spp., Legionella spp.), Mycoplasma spp., Chlamydia spp., Spirochaetaceae, Rickettsia spp. Erythromycin resistant gram-negative bacilli, including Escherichia coli, Pseudomonas aeruginosa, and Shigella spp., Salmonella spp.
 
Pharmacokinetics
 
Bioavailability of 30-65%. Distributed in most tissues and body fluids. Plasma protein binding is 70-90%. Metabolized in the liver, partly with the formation of inactive metabolites. Half-life - 1.4-2 hours is derived from bile and urine.
 
Statement
 
Infectious-inflammatory diseases caused by microorganisms sensitive to erythromycin, including diphtheria, pertussis, trachoma, brucellosis, a disease Legionnaires, sore throat, scarlet fever, otitis media, sinusitis, cholecystitis, pneumonia, gonorrhea, and syphilis. Treatment of infectious-inflammatory diseases caused by pathogens (eg staphylococci) are resistant to penicillin, tetracycline, chloramphenicol, streptomycin.
For external use: acne.
 
Dosing regimen
 
Set individually depending on the location and severity of the infection, the sensitivity of the pathogen. In adults use a daily dose of 1.4 grams Children under the age of 3 months - 20-40 mg / kg / day, aged from 4 months to 18 years - 30-50 mg / kg / day. Multiplicity of application - 4 times / day. The treatment course - 5-14 days after the disappearance of symptoms treatment should be continued for another 2 days. Take 1 hour before eating or 2-3 hours after eating.
Topical solution lubricate the affected skin.
The ointment is applied to the affected area and in diseases of the eye lay behind the lower eyelid. The dose, frequency and duration of application is determined individually.
 
Side effect
 
From the digestive system: nausea, vomiting, epigastric pain, cholestatic jaundice.
Allergic reactions: skin rash, hives, anaphylactic shock.
The effects caused by chemotherapeutic action: oral candidiasis, vaginal candidiasis.
 
Contraindications
 
Anamnestic information about jaundice, marked disturbances of liver function, hypersensitivity to macrolides.
 
Pregnancy and lactation
 
Erythromycin crosses the placenta, excreted in breast milk.
In the application of erythromycin in pregnancy should assess the intended benefits to the mother and the potential risk to the fetus. If necessary, use during lactation should decide on the termination of breastfeeding.
 
Cautions
 
With careful use in human liver and / or kidneys.
Drugs that increase the acidity of gastric juice and acidic drinks inactivate erythromycin. Erythromycin can not drink milk and dairy products.
 
 
Drug Interactions
 
With simultaneous use of erythromycin with lincomycin or chloramphenicol is a weakening of the latter.
With simultaneous use of erythromycin with theophylline, aminophylline, caffeine there is an increase in their concentration in blood plasma and thus increases the risk of toxic effects.
Erythromycin increases the concentrations of cyclosporine in the blood plasma and may increase the risk of nephrotoxicity.
 

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